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Advanced Physiology and Pathophysiology: Essentials for Clinical Practice

  • ISBN 9780826167552
  • Author: Tkacs, Nancy, PhD, RN
  • Publ Date: 2024-03-27
  • Edition: 2
  • Binding: Paperback / softback

$234.78
Sale: $211.30
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2020 AJN Book-of-the-Year Award Winner: Advanced Practice Nursing!


Concise and well-organized, this advanced physiology and pathophysiology text promotes deep understanding of key pathophysiological concepts and relates them to major disorders commonly seen in practice. It is distinguished by its stellar organization and writing that clarifies difficult-to-understand disease mechanisms. The second edition offers several new features that add to its value in preparing the student clinician to care for patients with a broad variety of disorders effectively. The second edition retains the inclusive language and conceptual organization central to the appeal and usefulness of the first edition. Coverage of new scientific advances update the original disease descriptions.


With the aim of preparing students to be well-informed and confident decision makers in primary care settings, the text provides the key knowledge required to master pharmacology for prescriptive practice. Addressing both healthy organ function and disease-associated changes, it details and illustrates the cellular structure and function of each organ system and mechanisms of associated major clinical disorders. It examines the reasons patients often present with particular symptoms, the rationale for ordering specific diagnostic tests and interpretation of the results, and common management strategies that proceed from the underlying pathology. The text is replete with case presentations to illustrate concepts, over 500 images, key points at the end of each chapter to reinforce knowledge, and a glossary defining correct terminology. Comprehensive instructor resources accompany the text. Purchase includes online access via most mobile devices or computers


New to the Second Edition:





Standardized template for pediatric and gerontology content for clarity

Expanded coverage of neonatal and pediatric development and vulnerabilities

Methylation patterns of cell-free DNA (epigenetics) in oncology practice

Expanded coverage of fluid and electrolyte balance

Physiology of pregnancy, labor, and delivery

Increased content on the social determinants of health

Introduction of the exposome concept in human disease

New content on biological and psychosocial aspects of human sexual development and variations relevant to LGBTQ+ centered care

COVID-19-related concerns



Key Features:





Includes comprehensive lifespan considerations with key insights from specialists in pediatric and geriatric pathophysiology

Integrates critical thinking questions and case studies to promote discussion and information synthesis

Provides unique Bridge to Clinical Practice in each chapter to translate science to practical patient care

Includes more than 500 images to illustrate complex scientific concepts

Summarizes content with key points at the end of each chapter
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