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Calcium Ions in Nerve Cell Function

  • ISBN 9780198546726
  • Author: KOSTYUK
  • Publ Date: 1992-03-19
  • Edition:
  • Binding: Hardback

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In this book, Professor Kostyuk reviews the progress that has been made in recent years in understanding the mechanisms by which calcium ions regulate nerve cell function. He covers all aspects of the topic, from the interaction of calcium ions with the external surface of the plasma membrane, to the function of transient changes in cytoplasmic calcium concentration. A major part of the book is devoted to a discussion of the different types of receptor- and voltage-operated calcium channels, and the basis of their selectivity, gating, inactivation, and pharmacological modulation. Professor Kostyuk then describes the development of calcium conductance during ontogenesis, before discussing the fate of calcium ions in the cell. He assesss the contribution made by the release of calcium from internal stores to cytoplasmic calcium transients, and analyzes mechanisms by which this release may be controlled.
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