Chemical Stability of Pharmaceuticals: A Handbook for Pharmacists

Author: Connors, Kenneth A.


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  • ISBN: 9780471879558
  • Author: Connors, Kenneth A.
  • Publ Date: 1986-11-19
  • Edition: 2
  • Pages: 864
  • Imprint: WILEY *#
  • Status: ACT
  • ID - 5965

Table of Contents :

PRINCIPLES. Stability Calculations. Interpretation of Kinetic Data. Hydrolysis and Other Acyl Transfers. Oxidation and Photolysis. Solid-State Chemical Decompostion. Strategy and Tactics of Stability Testing. STABILITY MONOGRAPHS. Appendixes. Index.


An accessible, single-source guide to the techniques, approximation methods and principles involved in studying drug stability and in making estimates of pharmaceutical product shelf-life. The book contains stability monographs of individual drugs, each reviewing cited data on kinetics of drug decomposition and methods for product stabilizations. Information on decomposiiton reactions, rate equations, pH-rate profiles, activation energies and formulation stability data are also featured.


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