Cancer: Principles & Practice of Oncology: Primer of the Molecular Biology of Cancer

Author: Vincent T DeVita, Jr, M.D. (Yale Cancer Center, Ya


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  • ISBN: 9781451118971
  • Author: Vincent T DeVita, Jr, M.D. (Yale Cancer Center, Ya
  • Publ Date: 2011-05-01
  • Edition:
  • Pages: 444
  • Imprint: LIPPINCOTT*#
  • Status: ACT
  • ID - 14035

Table of Contents :

Table of Contents Part I: General Principles 1. The Cancer Genome 2. Mechanisms of Genomic Instability 3. Epigenetics of Cancer 4. Telomeres, Telomerase, and Cancer 5. Cell Signaling, Growth Factors and their Receptors 6. Cell Cycle 7. Mechanisms of Cell Death 8. Cancer Metabolism 9. Angiogenesis 10. Invasion and Metastasis 11. Cancer Stem Cells 12. Biology of Personalized Cancer Medicine 13. Targeted Therapy with Small Molecule Kinase Inhibitors Part II: Molecular Biology of Individual Cancers 14. Head and Neck Cancers 15. Lung Cancer 16. Esophagus and Stomach 17. Pancreas Cancer 18. Liver Cancer 19. Colorectal Cancer 20. Kidney Cancer 21. Bladder 22. Prostate Cancer 23. Gynecologic Cancers 24. Breast Cancer 25. Endocrine Tumors 26. Sarcomas 27. Cutaneous Melanoma 28. Central Nervous System Tumors 29. Childhood Cancers 30. Lymphomas 31. Acute Leukemias 32. Chronic Leukemias


Drawn from the content of the new Ninth Edition of Cancer: Principles and Practice of Oncology, this unique publication brings together the basic scientific information on the molecular biology of cancer. The format is designed to be useful both to research scientists interested in the study of cancer and to oncologists who need to understand these new developments that are having a profound impact on the care of patients with cancer. Leading scientists and clinicians in the field of molecular biology and clinical oncology have lent their expertise to this project. The text has been divided into two parts. Part I includes thirteen chapters that deal with the general principles of the molecular biology of cancer that provide the basic framework for an understanding of the behavior of cancer cells. Part II includes an up-to-date description of how this new information has affected the understanding of the biology of 19 of the most common cancers, with an emphasis on how these new findings have been translated to impact the management of cancer patients. This distinctive text provides a single concise source of information for scientists and clinicians in this rapidly developing field.


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