Placenta, The: From Development to Disease

Author: Helen Kay


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  • ISBN: 9781444333664
  • Author: Helen Kay
  • Publ Date: 2011-04-05
  • Edition:
  • Pages: 360
  • Imprint: BLACKWELL *#
  • Status: ACT
  • ID - 13890

Table of Contents :

List of Contributors.
Part 1: Fetal origins of adult disease/programming.
1 Maternal Undernutrition and Fetal Programming: Role of thePlacenta (Louiza Belkacemi, D. Michael Nelson, Mina Desai andMichael G. Ross).
2 Cardiovascular Health and Maternal Placental Syndromes(Shahzya S Huda and Ian A. Greer).
Part 2: Placental development, physiology andimmunology.
3 Development and Anatomy of the Human Placenta (RoxaneRampersad, Mila Cervar-Zivkovic and D. Michael Nelson).
4 Immunologic Aspects of Pregnancy (Joan S. Hunt and MargaretG. Petroff).
5 Vascular Development in the Placenta (BertholdHuppertz).
6 Hypoxia and the Placenta (Stacy Zamudio).
7 Placental Metabolism (Nicholas P. Illsley).
8 Placental Hormones: Physiology, Disease and Prenatal Diagnosis(Jennifer M. McNamara and Helen H. Kay).
9 Placental Transfer in Health and Disease (Caroline Wrightand Colin P. Sibley).
10 Placental Fat Trafficking (Christina Scifres and YoelSadovsky).
11 Maternal-Fetal Cell Trafficking and Microchimerism (HilaryS. Gammill, Suzanne E. Peterson and J. Lee Nelson).
12 Imprinting in the Human Placenta (Shu Wen and Ignatia B.Van den Veyver).
13 Placental membranes and amniotic fluid retention (Marie H.Beall and Michael G. Ross).
Part 3: Examination of the placenta, membranes, cord.
14 Examination of the Placenta, Membranes and Cord (FrederickT. Kraus).
15 The Umbilical Cord (Raymond W. Redline).
16 Ultrasound Imaging and Doppler Studies of the Placenta(Methodius G. Tuuli and Anthony O. Odibo).
17 Magnetic Resonance Imaging and Positron Emission Tomographyof the Placenta (Christine H. Comstock and Helen H.Kay).
18 Chorionic Villous Sampling and Amniocentesis (Marion S.Verp).
19 Cordocentesis and Fetoscopy (Cristiano Jodicke and RayBahado-Singh).
Part 4: Research techniques to study the placenta.
20 Trophoblast Isolation and Culture (Mila Cervar-Zivkovicand Christina Stern).
21 Isolation and Culture of Human Umbilical Cord VeinEndothelial Cells (Yuping Wang).
22 Perfusion Technique for Studying the Placenta Cotyledon(Leslie Myatt).
23 Three-Dimensional Culture Modeling of the Placenta(Douglas A. Kniss and Teng Ma).
24 The Use of Ultrasound Contrast Agents in Placental Imaging(Jacques S. Abramowicz).
25 Microscopy and the Placenta (William E. Ackerman IV,Toshihiro Takizawa and John M. Robinson).
26 Proteomics & the Placenta (Gregory E. Rice).
27 Stable Isotope Methodologies for the Study of Transport andMetabolism In Vivo (Irene Cetin and Chiara Mando).
Part 5: Medical diseases and complications.
28 The Role of the Placenta in Autoimmune Disease and EarlyPregnancy Loss (Daniel L Jackson and Danny J. Schust).
29 The Placenta in Preterm Prelabor Rupture of Membranes andPreterm Labor (Chong Jai Kim, Roberto Romero and Sonia S.Hassan).
30 Diabetes and the Placenta (Ursula Hiden, Julia Froehlichand Gernot Desoye).
31 Placental Origins of Intrauterine Growth Restriction (IanP. Crocker).
32 The Placenta in Preeclampsia (Fiona Lyall).
33 Thrombophilia and the Placenta (Christina S. Han andMichael J. Paidas).
34 Infections in the Placenta (Samuel Parry).
35 Aneuploidy and Polyploidy (Dan Diego-Alvarez and Wendy P.Robinson).
36 Gestational Trophoblastic Disease and Placental Tumors(Katja Gwin and Aliya N. Husain).
37 Multiple Gestation and Twin-Twin Transfusion syndrome(Ramesha Papanna and Kenneth Moise).
38 Previa and Abruption (Helen H. Kay).
39 The Placenta as a Functional Barrier to Fetal Drug Exposure(Tatiana N. Nanovskaya, Gary D. V. Hankins and Mahmoud S.Ahmed).
40 Placental Drug Transport (Clifford W. Mason and Carl P.Weiner).
Part 6: Future clinical applications.
41 Umbilical Cord Blood Banking (Gilad A. Gross, Thinh Nguyenand Laura Meints).
42 Stem Cells from the Placenta (Thaddeus G. Golos).
43 Fetal DNA, RNA and prenatal diagnosis (Olav Lapaire andWolfgang Holzgreve).


The Placenta: From Development to Disease examines researchinto placental function and its clinical implications to provide aspringboard for improving clinical practice and enhancing medicalresearch. Influential information is extracted from the compellingnarrative by the use of 'take home' features including: * Clinical Pearls point to important issues in clinicalpractice * Research Spotlights - highlight key insights into placentalunderstanding * Teaching Points explain basic concepts for novicereaders

The Placenta: From Development to Disease is ideal forboth experienced clinicians and researchers and those new to thefield. Anyone who needs to understand the central importance of theplacenta in the well being of their maternal and fetal patientsshould read this book.


"At a time when there is so much overlap in the realm of medicalbooks, this one stands out as a unique and worthwhile contributionto the field. From the clarity of its layout to its detaileddescriptions to its in-depth illustrations, it is a great referencefor anyone interested in the physiology of pregnancy." (Doody's, 19August 2011)

Author Biography:

Helen Kay, MD, Department of Obstetrics and Gynecology,Washington University School of Medicine, St. Louis, MO, USA
D. Michael Nelson, MD, PhD, Department of Obstetrics andGynecology, Washington University School of Medicine,St. Louis, MO, USA
Yuping Wang, MD, PhD, Departments of Obstetrics andGynecology, and Molecular and Cellular Physiology, LouisianaState University Health Sciences Center Shreveport,Shreveport, LA, USA


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