Muscle Biopsy: A Practical Approach

Author: Victor Dubowitz


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  • ISBN: 9780702043406
  • Author: Victor Dubowitz
  • Publ Date: 2013-04-02
  • Edition: 4
  • Pages: 592
  • Imprint: SAUNDERS *#
  • Status: ACT
  • ID - 7014

Table of Contents :

Section 1 The Biopsy: Normal and Diseased Muscle 1. The procedure of muscle biopsy 2. Histological and histochemical stains and reactions 3. Normal muscle 4. Definition of pathological changes seen in muscle biopsies 5. Ultrastructural changes in diseased muscle 6. Immunohistochemistry 7. How to read a biopsy Section 2 Pathological Muscle: Individual Diseases 8. Classification of neuromuscular disorders 9. Neurogenic disorders 10. Muscular dystrophies and allied disorders I: Duchenne and Becker muscular dystrophy 11. Muscular dystrophies and allied disorders II: limb-girdle muscular dystrophies 12. Muscular dystrophies and allied disorders III: congenital muscular dystrophies 13. Muscular dystrophies and allied disorders IV: Emeryf{Driefuss muscular dystrophies and Bethlem myopathy 14. Muscular dystrophies and allied disorders V: facioscapulohumeral dystrophy, myotonic dystrophy, oculopharyngeal muscular dystrophy 15. Congenital myopathies 16. Myofibrillar myopathies 17. Metabolic myopathies I: glycogenoses 18. Metabolic myopathies II: lipid related disorders and mitochondrial myopathies 19. Endocrine disorders 20. Ion channel disorders 21. Myasthenic syndromes 22. Inflammatory myopathies 23. Toxic and drug-induced myopathies Russell Lane, Charing Cross Hospital Appendix 1. Glossary of commonly used terms References Index


2014 BMA Medical Book Awards Highly Commended in Pathology category! Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. Authored by Dr. Victor Dubowitz, an internationally renowned figure in the field of muscle disease, this medical reference book takes an integrated approach to diagnosis and assessment of muscle biopsies that includes clinical, genetic, biochemical, and pathological features. It's the comprehensive, up-to-date coverage you need to evaluate muscle disorders with confidence.


"The third edition of this book...has surpassed my expectations. The quality of the book overall is excellent, from the production and layout to the illustrations, diagrams and index. The range of muscle diseases included spans both adults and children, with an integrated approach to diagnosis including clinical, genetic, biochemical and pathological features. Overall, this book has been a highlight of the past year for me. It deserves to do very well indeed and will be of immense value beyond its target readership." -BMA Awards, 2007, Review of the 3rd Edition "The book is aimed at diagnostic pathologists and the authors have made a sensible and valid attempt to harmonise classical nomenclature with the new advances in genetics that threaten to overturn previous attempts at classifying muscle disease. Overall, this is a well written and comprehensive textbook of muscle pathology that will be of invaluable assistance to laboratories reporting muscle pathology." Reviewed by: Dr Ian S Scott Consultant Neuropathologist Queen's Medical Centre Nottingham? Date: Jan 2015


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